MCQs PAGE - 02

❂ Amphotericin B is obtained from which microorganism?

1) Staphylococci

2) Streptomyces

3) Blastomyces

4) Cryptococcus

❂ Identify dimorphic fungi.

1) Cryptococcus neoformans

2) Candida albicans

3) Histoplasma capsulatum

4) Aspergillus fumigatus

❂ Griseofulvin isolated from ___________________________culture.

1) Penicillium notatum

2) Penicillium crysofulvum

3) Penicillium griseus

4) Penicillium griseofulvum

❂ Echinocandin B derived from________________________.

1) Aspergillus nidulans

2) Aspergillus niger

3) Penicillium notatum

4) Streptomyces

❂ Which is a synthetic antifungal drug?

1) Echinocandin B

2) Caspofungin

3) Ketoconazole

4) Amphotericin B

❂ Which one is active metabolite of azathioprine?

1) Disulfiram

2) Metronidazole

3) Mercaptopurine

4) Clopidogrel

❂ The following antiepileptic drugs have anxiolytic properties except one:

1) Gabapentin

2) Pregabalin

3) Valproate

4) Phenytoin

❂ Which substance is an analogue of somatostatin?

1) Exenatide

2) Octreotide

3) Glipizide

4) Tolbutamide

❂ How many liters of urine voided in 24 hr from kidney in usual conditions?

1) 2.5 litres

2) 1.5 litres

3) 3.5 litres

4) 1.2 litres

❂ Which diuretic compete with aldosterone?

1) amiloride

2) trimterene

3) furosemide

4) spironolactone

❂ Nicotine is act on acetylcholine ______________________receptor.

1) α3,β2

2) α4,β2

3) α3,β1

4) α4,β1

❂ Which is the medicine that reduces the production of thyroid hormone?

1) Livothyroxine

2) Livothyronine

3) Carbimazole

4) Radio iodine

❂ The following drugs are used in the treatment of hyperthyroidism except one:

1) Carbimazole

2) Propylthiouracil

3) Livothyronine

4) Radio iodine

❂ Which drug is used in nephrogenic diabetes insipidus?

1) Bumetanide

2) Bendroflumethiazide

3) Furosemide

4) Trimterene

❂ Which is a selective COX-1 (cyclooxygenase) inhibitor?

1) Celecoxib

2) Piroxicam

3) Ibuprofen

4) Flurbiprofen

❂  70 kg man has __________grams of iron in his body.

1) 5

2) 4

3) 0.7

4) 0.5

❂ Choose the option based on the amount of iron.

1) Haemoglobin > transferrin > cytochromes > myoglobin

2) Haemoglobin > myoglobin > cytochromes >vtransferrin

3) Hytochromes > haemoglobin > myoglobin > transferrin

4) Cytochromes > myoglobin > haemoglobin > transferrin

❂ Which is a Vitamin K antagonist?

1) Hirudin

2) Tirofiban

3) Warfarin

4) Clopidogrel

❂  Kininogen is a________________________protein.

1) Plasma β globulin

2) Plasma α globulin

3) Plasma δ globulin

4) Plasma γ globulin

❂ Which is a selective β-1 receptor antagonist?

1) Des-Arg Hoe 140

2) Icatibant

3) Kallikrein

4) Kininogen

❂ Which is a selective β-2 receptor antagonist?

1) Kallikrein

2) Des-Arg Hoe 140

3) Kininogen

4) Icatibant

❂ Which substance is a 5-lipoxygenase inhibitor?

1) Montelukast

2) Glucocorticoids

3) Zileutin

4) Dimaprit

❂ Which substance is a renin inhibitor?

1) Captopril

2) Enalkiren

3) Spironolactone

4) Losartan

❂ Which substance is an ACE (acetylcholinesterase) inhibitor?

1) Enalkiren

2) Spironolactone

3) Clonidine

4) Captopril

❂ In the following diseases conditon ACE (angiotensin converting enzyme) inhibitor role is important except one : 

1) Hypertention

2) Hypotension

3) Cardiac failure

4) Diabetic nephropathy

❂ The following medicines are angiotensin-2 receptor antagonists except one:

1) Losartan

2) Candesartan

3) Captosartan

4) Irbesartan

❂ Which anti-fungal medicine produces side effects like Stevens Johnson syndrome?

1) Miconazole

2) Flucytosine

3) Fluconazole

4) Itraconazole

❂  _____________________ is a prodrug of penciclovir.

1) Valganciclovir

2) Ganciclovir

3) Valaciclovir

4) Famciclovir

❂ Platelets have a low affinity for the________________receptor.

1) IgD

2) IgE

3) IgM

4) IgG

❂ Which drug is an integrase inhibitor?

1) Zanamivir

2) Ratelgravir

3) Oseltamivir

4) Tenofovir

❂ Which drug inhibits the neuraminidase enzyme?

1) Maraviroc

2) Ratelgravir

3) Zanamivir

4) Enfurvitide

❂ Which species are responsible for eye disease and infertility?

1) Chlamydia trachomatis

2) Treponema pallidum

3) Bacillus anthracis

4) Clostridium tetani

❂ Which anthelmintic drugs have nicotine-like action?

1) Ivermectin

2) Diethyl carbamazine

3) Levamisole

4) Niclosamide

❂ Which histamine H2 receptor antagonists cause gynecomastia side effects?

 1) Ranitidine

2) Nizatidine

3) Famotidine

4) Cimetidine

❂ Which H2 antagonist is not taken intramuscularly and intravenously?

1) Ranitidine

2) Nizatidine

3) Famotidine

4) Cimetidine

❂ Which drug potentiates anticoagulants and tricyclic anti-depressants?

1) Omeprazole

2) Esomeprazole

3) Cimetidine

4) Ranitidine

❂ Which receptor does gastrin act on?

1) SSR 2 ( signal sequence receptor )

2) CCK2 (cholecystokinin )

3) M3 (Muscarinic ) receptor

4) EP2/3 (Prostaglandin) receptor

❂ In which cardiac action potential phase do class IV antiarrhythmic drugs act?

1) Pacemaker potential (phase 4)

2) Rapid depolarization (phase 0)

3) Plateau (phase 2)

4) Depolarization (phase 3)

❂ Which diuretic acts on the distal tubule?

1) Hydrochlorothiazide

2) Spironolactone

3) Eplepenone

4) Furosemide

❂ Somatriptan acts on the ________________________receptor.

1) 5-HT1A

2) 5-HT1D

3)  5-HT2 

4) 5-HT3

❂ Which medicine is used for depression?

1) Pizotifen

2) Buspirone

3) Fluoxetine

4) Somatriptan

❂ Which medicine is used for anxiety?

1) Buspirone

2) Somatriptan

3) Ondansetron

4) Fluoxetine

❂ Which medicine is used for the treatment supraventricular tachycardia?

1) Atropine

2) Adrenaline

3) Adenosine

4) Digoxin

❂ Which medicine is used in the prevention of migraine?

1) Somatriptan

2) Fluoxetine

3) Ondansetron

4) Pizotifen

❂ Which drug is responsible for producing jaundice?

1) Chlorpromazine

2) Clozapine

3) Olanzapine

4) Flupentixol

❂ Which antipsychotic drug causes agramocytosis?

1) Amisulpride

2) Flupentixol

3) Clozapine

4) Decanoate

❂ The following are typical antipsychotic drugs except one:

1) Promazine

2) Chlorpromazine

3) Haloperidol

4) Clozapine

❂ Which is a long acting opioid antagonist?

1) Naltrexone

2) Naloxone

3) Pentazocine

4) Alvimopan

❂ Which opioid analgesic is primarily used in postoperative pain?

1) Codeine

2) Tramadol

3) Dextropropoxyphene

4) Remifentanil

❂ Which drug has mixed agonist-antagonist (K agonist and mu receptor antagonist or weak partial agonist) property?

1) Etorphine

2) Codeine

3) Nalorphine

4) Dextropropoxyphene

❂ MODY (maturity onset diabetes of the Youth) is part of which type of diabetes?

1) TYPE-2 diabetes

2) TYPE-1 diabetes

3) Gestational diabetes

4) Diabetes insipidus

❂  Which cytotoxic drug is used as an antiemetic agent?

1) Nabilone

2) Tamoxifen

3) Etoposide

4) Paclituxel

❂  Which drug is used in the treatment of germ cell tumors?

1) Lomistine

2) Cisplatin

3) Cyclophosphamide

4) Busulfan

❂ The following antimetabolite drugs act on the purine pathway except one:

1) Fludarabine

2) Cladibrime

3) Tegafur

4) Nelarbime

❂  Nicotinic acid acts on which receptor to produce its lipid-lowering property?

1) HM73A

2) HM74A

3) HM71A

4) HM72A

❂  HMG-COA reductase full form  is  __________________________________________.

1) 3-Hydroxy -4 methyl glutaryl -coA reductase

2) 3-Hydroxy-3 methyl glutaryl -coA reductase

3) 4-Hydroxy -4 methyl glutaryl -coA reductase

4) 4-Hydroxy -3 methyl glutaryl -coA reductase

❂  Which condition is a risk factor for atheromatous disease?

1) Raised low density cholesterol 

2) Raised high density cholesterol 

3) Reduced high density cholesterol 

4) Diabetes mellitus

5) More than one option

❂ What is the particle size  of HDL (high density lipoprotein ) ?

1) 7-20 nm

2) 20-30 nm

3) 30-80 nm

4) 100-1000 nm

❂  Which lipoprotein contains the apoB-48 protein?

1) HDL particle

2) VLDL particle

3) LDL particle

4) Chylomicrons

❂  Which lipoprotein contains the apoB-100 protein?

1) LDL particle

2) HDL particle

3) VLDL particle

4) Chylomicrons

❂  Which medicine is used in Raynaud's disease?

1) Carvedilol

2) Bisoprolol

3) Nifedipine

4) Bosentan

❂  The normal systolic pulmonary pressure range in adults is _________________.

1) 5 mmHg

2) 15 mmHg

3) 10 mmHg

4) 20 mmHg

❂  Which antihypertensive drug class has the highest level of impotence side effects? 

1) ACE (Angiotensin-converting-enzyme) inhibitors

2) Thiazide diuretics

3) AT1 (angiotensin II type 1 receptor) antagonists

4) B-adrenoceptor antagonist

❂  which antihypertensive drug class possess highest postural hypotension side effect?

1) thiazide diuretics

2) ACE inhibitors

3) Alpha1-adrenoceptor antagonists

4) B-adrenoceptor antagonists

❂  Which drug is a renin inhibitor?

1) Losartan

2) Ramipril

3) Hydralazine

4) Aliskiren

❂  The following drugs are directly acting vasodilators except one :

1) Nifedipine

2) Diltiazem

3) Ramipril

4) Verapamil

❂  Which drug increases guanyl cyclase activity?

1) Epoprostenol

2) Glyceryl trinitrate

3) B2-adrenoceptor

4) Adenosine