MCQs PAGE - 05
❂ Which drug acts on both adrenoceptor and oxytocin receptor?
1) Ergometrine
2) Atosiben
3) Ritodribe
4) Salbutamol
❂ Angiotensin-2 is _____________.
1) Hecapeptide
2) Octapeptide
3) Decapeptide
4) Tetrapeptide
❂ Which hypoglycaemic drug is highly bound to plasma proteins?
1) Glibenclamide
2) Glipizide
3) Tolbutamide
4) Pioglitazone
❂ Hydrochlorothiazide blocks _____________________.
1) NA+ -- K+ Symporter
2) NA+ -- H+ Symporter
3) Na+ -- Cl- Symporter
4) K+ -- Cl- Symporter
❂ Which antiarrhythmic works by blocking both sodium and potassium channels?
1) Flecainide
2) Tocainide
3) Quinidine
4) Lignocaine
❂ Which vitamin precursor is ergosterol?
1) Vitamin A
2) Vitamin B12
3) Vitamin D
4) Vitamin H
❂ What is the normal weight of thyroid gland?
1) 135 - 140 g
2) 12-20 g
3) 105 -120 g
4) 70 -80 g
❂ Which pathway has the highest amount of dopamine?
1) Mesolimbic pathway
2) Nigrostriated pathway
3) Mesocortical pathway
4) Tuberoimfundibular
❂ Phospholipids are activated by __________.
1) Tryptophan
2) Trypsin
3) Tyrosine
4) Tyramine
❂ Which vitamin is synthesized by flora bacteria?
1) Vitamin A
1) Vitamin B12
3) Vitamin H
4) Vitamin K2
❂ Which neurotransmitter was first identified?
1) Dopamine
2) Noradrenaline
3) Acetylcholine
4) 5-HT (Serotonin)
❂ Amlodipine drug acts on _____________________.
1) Calcium channel
2) Sodium channel
3) Chloride channel
4) Potassium channel
❂ Which medicine causes pain in the bladder?
1) Morphine
2) Ketamine
3) Nicotine
4) Cocaine
❂ The Reticuloendothelial system is ___________________________.
1) Part of the Otorhinolaryngology System
2) Part of the Immune system
3) Works as a vector for drug transport
4) 2&3 both
❂ In which organ is the Kupffer cell present?
1) Spleen
2) Bone
3) Liver
4) Brain
❂ A newborn baby has _________ bones.
1) 206
2) 245
3) 305
4) 289
❂ Which is the largest cell in our body?
1) Skin cell
2) Liver cell
3) Neuron cell
4) Sperm cell
❂ Which one is suitable for the word pancytopenia?
1) Decreased WBC (white blood cell)
2) Increase RBCs and WBCs
3) Decreased WHOLE blood components cells
4) Increased platelet cell
❂   select appropriate pair :
                          [DRUG]
                      ©) Benztropine
                      ¥} Vigabatrin
                      ¢} Terbinafine
                      €} Mupirocin
                 [MECHANISM OF ACTION]
  π) It inhibit squalene epoxidase
        enzyme
 ¶) It inhibit staphylococcap isoleucyl
      tRNA  synthetase
∆) It block muscarinic receptor
£) It inhibit GABA transaminase enzyme
Options:
1) ©-£,¥-∆,¢-π,€-¶
2) ©-∆,¥-£,¢-π,€-¶
3) ¥-π,©-£,¢-π,€-¶
4) ¥-£,©-π,¢-∆,€-¶
❂ Which is vasopressin related diabetes?
1) Diabetes Mellitus type 1
2) Diabetes Mellitus type 2
3) Diabetes Insipidus
4) Gestational Diabetes
❂ What is a normal BMI (Body Mass Index) value?
1) 27- 32 kg /m2
2) 19-25 kg /m2
3) 38-40 kg /m2
4) 15 -19 kg/m2
❂ Select the correct statement for 5-HT (serotonin)
A: Tigaserod used in IBS ( inflammatory bowel syndrome)
B: LSD (Lysergic acid diethylamide) is also act on serotonin
C: Bromocriptine is potent 5-Ht receptor agonist
D: 5-HT receptor plays an important role in migraine treatment
Options:
1) A&B true, C&D false
2) C&D true, A&B false
3) A, B, C true, C false
4) A, B, C true, D false
❂ Hepatitis B virus is a ____________________ virus.
1) Single stranded RNA
2) Double stranded DNA
3) Both DNA and RNA 
4) Single stranded RNA
❂ Hemochromatosis is a _________ disease.
1) Spleen
2) Kidney
3) Liver
4) Brain
❂ What does dysmenorrhea mean?
1) High blood loss 
2) Absence of menstrual cycle
3) Pain during menstruation
4) Late menstrual cycle
❂ Select the inappropriate statement for epilepsy.
1) Role of Voltage gated Ca++ channel is important in epilepsy
2) Role of Voltage gated K+ channel is important in epilepsy
3) Role of Voltage gated Cl- channel is important in epilepsy
4) Role of Voltage gated Cl- channel is important in epilepsy
5) All of the above options are true
❂ The following drugs only inhibit 5-HT reuptake except one:
1) Venlafexine
2) Fluoxetine
3) Sertraline
4) Paroxetine
❂ Which type of Ca++ channel plays an important role in epileptic conditions? 
1) P type
2) T type
3) Q type
4) R type
❂ What is mechanism action of vinorelbine ?
1) It inhibit topoisomerase 2 enzyme
2) It inhibit tubulin protein or mitosis
3) It inhibit renin enzymatic action
4) It inhibit K+ channel conductance
❂ Which is the natural anti-arthritic medicine?
1) Allopurinol
2) Indometacin
3) Probenecid
4) Colchicine
❂ Which diuretic agent acts as an osmotic agent?
1) Mannitol
2) Spironolactone
3) Furosemide
4) Chlorothiazide
❂ All the following medicines act on the voltage gated channel and give anti-dyarrhythmic action except one:
1) Sotalol
2) Verapamil
3) Lidocaine
4) Propranolol
❂ Identify the mechanism of action of macrolides?
1) It inhibit 30 S ribosomal RNA
2) It inhibit 50 S ribosomal RNA
3) It inhibit DNA gyrase enzyme
4) It inhibit topoisomerase enzyme
❂ Which receptor does glycine act on?
1) NMDA receptor 
2) AMPA receptor
3) KAINATE receptor
4) GABA -A receptor
❂ Which is an anaerobic bacteria?
1) Staphylococcus aureus
2) Streptococcus pyogenes
3) Helicobacter pylori
4) Clostridium difficile
❂ Which IV (intravenous) anesthetic agent has the highest receptor binding?
1) Diazepam
2) Ketamine
3) Propofol
4) Thiopental
❂  Penicillamine is produced by the ____________of penicillin.
1) Reduction
2) Oxidation
3) Methylation
4) Hydrolysis
❂  Which is a long acting sulfonamide?
1) Sulfadiazine
2) Sulfisoxasole
3) Sulfadiazine
4) Sulfamethoxazole
❂ which is the rescue medicine for Parkinson's disease?
1) Pergolide
2) Pramipexole
3) Memantine
4) Bromocriptine
❂ select unsuitable option for AIDS:
1) AIDS is caused by RNA virus
2) The structure of the HIV virus consists of the gp120 and gp40 proteins
3) Zidovudine is the most widely used anti-HIV drug
4) HIV virus attacks the body's CD4 cells
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