MCQs PAGE - 09

❂ Choose the appropriate option:

A :   Both β-adrenoceptor agonist and β-adrenoceptor antagonist drugs are beneficial in combination

B : Both the drugs minoxidil and lignocaine are potassium channel blockers

C : Infiltration anesthesia method is convenient for painless childbirth

D : Loop diuretics have lesser effect in patients with renal dysfunction

Options:
1) A, B, C true, D false

2) A, B, C, D all are true

3) A, B, C false, D True

4) A, B, C, D all are false

❂ Select the wrong statement : 

1) GABA has more subreceptor than glutamate

2) GHB (gamma hydroxy butyric acid) is a metabolite of GABA

3) Aspartate and Ketamine both act on the glutamate receptor

4) Baclofen is a GABA agonist drug


❂ Which is a mineralocorticoid?

1) ACTH ( Adrenocorticotrophin hormone)

2) Prolactin

3) Somatostatin

4) Aldosterone



❂ Which anti-diabetic drug affects the thyroid gland?

1) Glitazones

2) Repaglinide

3) Tolbutamide

4) Chlorpropamide



❂ Which drug is 3-methoxy morphine?

1) Oxycodone

2) Codeine

3) Diamorphine

4) Methadone



❂ The following drugs are used in the treatment of alcohol addiction except one:

1) Disulfiram

2) Acamprosate

3) Naltrexone

4) Varenicline



❂ Which is normal patient range of phase-2 clinical studies?

1) 1000-1500

2) 100-300

3) 20-60

4) 500-1000



❂ Human cell surface molecules possess which type of electric charge?

1) negative charge

2) positive charge

3) neutral charge

4) major positive charge and minor negative charge



❂ DNA  form of RNA virus is called________.

1) provirus

2) mRNA

3) virion

4) oncogenic RNA



❂ Following all are virus able to infect non-dividing cells exception:

1) HTLV-1

2) rous sarcoma virus

3) foamy virus

4) HIV-1



❂ Which component is not involved in inflammation reaction?

1) interleukins

2) interferons

3) ghrelin

4) cytokines



❂ Which NSAIDS selective COX -2(cyclooxygenase -2) enzyme inhibitor?

1) indometacin

2) paracetamol

3) aspirin

4) celecoxib



❂ Select appropriate pair

              [DRUG]

         1) STATINS

         2) SULFONAMIDE

         3) ACE INHIBITOR

         4) CIMETIDINE

         5) CHLORAMPHENICOL

        [ ADVERSE DRUG REACTION]

          A) crystal urea

          B) gynecomastia

          C) grey baby syndrome

          D) rhabdomyolysis

          E) dry cough

Options:
1) 1-A,2-D,3-B,4-E,5-C

2) 1-D,2-A,3-E,4-B,5-C

3) 1-C,2-E,3-B,4-D,5-A

4) 1-A,2-C,3-B 4-E,5-D



❂ Sarcoma is _____________type of cancer.

1) lung

2) brain

3) skin

4) liver

5) spleen



❂ Growth hormone release from which site?

1) adrenal gland

2) pituitary gland

3) hypothalamus

4) nigrostriatal region



❂ Which drug is useful to delay early pregnancy?

1) ergometrine

2) ritodribe

3) oxytocin

4) prostaglandin analogue



❂ Select wrong statement for ethanol:

1) ethanol consumption cause dependence

2) ethanol absorption also occur by stomach

3) buproprion is used in ethanol dependence treatment

4) in methanol poisoning ethanol work as antidote



❂ Colistin is which class antibiotic?

1) aminoglycisides

2) quinolones

3) polymixins

4) BETA-lactum antibiotics



❂ Following  component  or part synthesize  PAF (platelet activation  factors) exception:

1) kidney

2) liver

3) WBCs

4 ) RBCs

5) 2& 4

❂ Select  wrong statement  for PAF (platelet activation  factor )

1) it constrict blood vessels

2) PAF act on My receptor  and contraction occur

3) PAF is also responsible  for release  of leukotrienes

4) Acetyl coach is also participate in PAF activation  or synthesis



❂ Which component  administration   is Hazardous  in vitamin B1(thiamine )  deficient  patient ?

1) lactose

2) glucose

3) galactose

4) arginine



❂ In which disease  condition niacin amide is ineffective?

1) hyperinsulanemia

2) hyperthyroidism

3) hypercholesterolemia

4) hypercalceamia


❂ What is reason to produce green colour  in jaundice  patients?

1) reduction  of bilirubin  to biliverdin

2) oxidation of bilirubin  to biliverdin

3) acetylation of bilirubin to biliverdin

4) methylation  of bilirubin to  biliverdin



❂ What is chemical  structure  of bilirubin ?

1) trypyridine

2) tetrapyridine

3) tetrapyrrole

4) trypyrrole



❂ How many  amino acid comprise to form substance  P structure?

1) 12 amino acid

2) 11 amino acid

3) 10 amino acid

4) 9 amino acid



❂ Select appropriate answer

X : benzodiazepines work on Gamma amino butyric acid receptor

Y : flumazenil is used for benzodiazepines overdose treatment

Z : benzodiazepines possess convulsant effect

V : benzodiazepines does not affect on respiratory tract

Answers:

1) X and Y false, Z and V true

2) X and Z true ,Y and V false

3) X and Z false ,Y and V true

4) X and Z true, Z and V false

❂ Which vitamin is insoluble in water and fat ?

1) vitamin A

2) vitamin K

3) vitamin H

4) vitamin E



❂ Select appropriate pair

                        [ X ]

$) Ethosuximide

€) phenytoin

£) tadalafil

¥) donepezil

¢) colchicine



          [ Y ]

÷) Alzheimer's disease

%) gout

#) erectile dysfunction

*) absence seizure

=) tonic clonic seizure



Answers:
1) € - #, $ - *,¥-%,¢-÷,£ -=

2) € - *,$ -# ,¥ -% ,© -÷,£ -=

3) $- = ,€ -* ,£-#,¥ - ÷ ,¢ - %

4) $ - *,€ - = ,£ -# ,¥ -÷ ,¢ -%



❂ Fibrin genetic mutation  leadS to __________________disease  condition.

1) cushing syndrome

2) black  fever

3) marfan syndrome

4) cystic fibrosis



❂ Kost mann's syndrome is related to  ___________blood component.

1) basophil

2) platelets

3) neutrophile

4) WBCs

5) RBCs



❂ Select appropriate  options

X: mycobacteria genavense organism is grow under semisolid  media

Y: dobutamine  drug possess  potent chronotropic  effect

Z: in sickle  cell syndrome  Beta- globin mutation  occur.

P: in chikungunia disease  decrease  level of Aspartate  amino transferase

Q: micro villar cells are present  in nasal part

R: Gas gangrene produced by cloatridium species

options :
1) X,Z,P are true, Y , O, Q, R are false

2) R, Q, P, OR are false  , Z , Y,X are true

3) X, Y, P are false  , Z , O, Q, R are true

4) X, Y, P are true , Z , O, Q, R are false



❂ Which drug is used to diagnose  of myasthenia gravis?

1) ampicillin

2) edrophonium

3) methyldopa

4) nitroglycerin


❂ How long it take for aspirin to reach peak plasma concentration?

1) 3 hour

2) 2  hour

3) 1 hour

4) less than 1 hour

❂ Which is the antitumor antibiotic drug?

1) Clarithromycin

2) Dactinomycin

3) Camptothecin

4) Vincristine

❂ Select the correct option for the scientific name of Rabbit :

1) Rattus norvegicus

2) Oryctolagus cuniculus

3) Cavia porcellus

4) Mus musculus

❂ Which is the best animal for pyrogen test?

1) Mouse

2) Dog

3) Rabbit

4) Guinea pig

5) Rat

❂ Which is the biguanide class hypoglycemic agent?

1) Glimepiride

2) Pioglitazone

3) Metformin

4) Acarbose